Tuesday, November 25, 2008

Real-Time DNA Sequencing from Single Polymerase Molecules



Just coming down the line now is this paper in Science on single molecule sequencing using fluorescent bases incorporated by DNA polymerase.  Besides the huge "Wow!" factor, this paper comes out of Pacific Biosciences in Menlo Park, featuring two Block lab alumni, Adrian Fehr and Ravi Dalal.  In addition, I just noticed that the first first-author (as opposed to the six other first authors) is none other than John Eid, one of my contemporaries at U of I, who worked with Enrico Gratton in the Laboratory for Fluorescence Dynamics (now at UC Irvine).

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